miRNA and non-coding long RNA microarrays«please contact us for all cost inquiriesMicroRNAs (miRNAs) are small, single stranded RNA molecules encoded in the genomes of plants and animals. These highly conserved, ~20-mer RNAs regulate the expression of genes by binding to the 3'-untranslated regions (3'-UTR) of specific mRNAs with the aid of RISC complex (see figure below). miRNAs have been found to be key regulators in cell growth, cell death, metabolism and cell differentiation. They are becoming increasingly important as more information is discovered in their link to such diseases as cancer, viral disease and neurodevelopment. A non-coding RNA (ncRNA) is a functional RNA molecule that is not translated into a protein. The number of ncRNAs encoded within the human genome is unknown, however recent transcriptomic and bioinformatic studies suggest the existence of thousands. Recent recognition that long ncRNAs function in various aspects of cell biology has focused increasing attention on their potential to contribute towards disease aetiology. A handful of studies have implicated long ncRNAs in a variety of disease states and support an involvement and co-operation in oncogenesis.
* Click on a product or service in the table to see more info below
Commercially available miRNA arrays from: Agilent has developed a microarray-based application for studying microRNAs (miRNAs) that combines a unique miRNA direct labeling method with their innovative probe design and established high-performance SurePrint inkjet synthesis technology. Sample Requirement: Agilent miRNA arrays require 100ng total RNA per array (50ng for 2 color arrays). Click here to see our Agilent certified services page.
|
|||||||
 |
|
 |
|
|
|