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 Understanding
the hidden story within large amounts of high throughput
data along with the ever-evolving genomic and proteomic
resources can be very daunting.
The Microarray facility has a committed team of bioinformaticians
with extensive experience in microarray technology, informatics
and molecular biology.
We offer side-by-side guidance and training in all areas
whether it’s instruction on how to use the latest
versions of cutting edge software suites or customized
statistical analysis for presentations and publication.
We have developed several in- house analysis programs
to deal with unique datasets such as SNP and mRNA.
We also offer assistance in publishing your data to public
microarray data repositories such as NCBI’s Gene
Expression Omnibus (GEO) in MIAME compliant form.
All members of our facility work together on the research
and development of our services in order to provide to
highest quality arrays and most robust data analysis.
Software includes:
• GeneSpring from Agilent Technologies
• CGH Analytics from Agilent Technologies
• Acuity from Molecular Devices
• R and BioConductor
• Ingenuity Pathways Analysis
Comprehensive microarray analysis support and bioinformatics
services include:
• custom-tailored analyses for individual questions
• statistical expertise in discussion of results
• non-linear data normalization
• various statistical analyses for differentially
expressed genes
• various visualizations of data,
• clustering analyses (all commonly used methods)
• the incorporation of annotations, gene ontology
(GO) information, and functional group analysis
• finding and visualizing pathways for differentially
expressed genes
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