Protein Microarrays

Protein microarrays are used to identify protein-protein interactions, to identify the substrates of protein kinases, or to identify the targets of biologically active small molecules. The most common protein microarray is the antibody microarray, where antibodies are spotted onto the protein chip and are used as capture molecules to detect proteins from cell lysate solutions.

We offer custom protein microarray assay development services including experimental design, microarray printing, sample conjucation, and data acquisition and analysis.

Our facility offers the two major classes of protein microarray formats, forward phase arrays and reverse phase arrays, depending on whether the targets of interest are captured from solution phase or bound to the solid phase. The type of assay and detection method of interest will determine what surface chemistry is used to manufacture the microarrays.

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You are welcome to contact us for any protein microarray project.

Forward phase arrays

In collaboration with Kinexus Bioinformatics, our facility has adapted a proteomics tool to the microarray technology for tracking large numbers of cell signaling proteins. The resulting antibody microarray monitors the activity changes in target signaling proteins in addition to their expression levels in dye-labeled cell and tissue lysates for up to 650 different antibodies that have been arrayed on plastic slides.

This product is exclusively produced for Kinexus Bioinformatics Corp. For more information see the company website.